A New Genomic Frontier for Foodborne Disease Investigation in Australia

Grant number: 1129770 | Funding period: 2017 - 2019

Completed

Abstract

Foodborne diseases caused by bacteria such as Salmonella and Campylobacter are a huge public health problem, both in Australia and globally. Current methods used to investigate foodborne disease may not be sensitive enough to track foodborne outbreaks, and may not even detect them in the first place. We propose using cutting-edge molecular techniques to investigate foodborne outbreaks, and we think that using these methods will enable outbreaks to be interrupted at a much earlier stage.

Related publications (7)

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Evolutionary dynamics of multidrug resistant Salmonella enterica serovar 4,[5],12:i:- in Australia

DJ Ingle, RL Ambrose, SL Baines, S Duchene, A Gonçalves da Silva, DYJ Lee, M Jones, M Valcanis, G Taiaroa, SA Ballard, MD Kirk, BP Howden, JS Pearson, DA Williamson

2021-12-01

Salmonella enterica serovar 4,[5],12:i:- (Salmonella 4,[5],12:i:-) is a monophasic variant of Salmonella Typhimurium that has emer..

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Genomic diversity of antimicrobial resistance in non-typhoidal Salmonella in Victoria, Australia

CM Sia, SL Baines, M Valcanis, DYJ Lee, A Gonçalves da Silva, SA Ballard, M Easton, T Seemann, BP Howden, DJ Ingle, DA Williamson

2021-01-01

Non-typhoidal Salmonella (NTS) is the second most common cause of foodborne bacterial gastroenteritis in Australia with antimicrob..

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Emergence and divergence of major lineages of shiga-toxin-producing escherichia coli in Australia

DJ Ingle, AG da Silva, M Valcanis, SA Ballard, T Seemann, AV Jennison, I Bastian, R Wise, MD Kirk, BP Howden, DA Williamson

2019-05-01

Shiga-toxin-producing Escherichia coli (STEC) infection is an important global cause of foodborne disease. To date however, genomi..

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Informal genomic surveillance of regional distribution of Salmonella Typhi genotypes and antimicrobial resistance via returning travellers

DJ Ingle, S Nair, H Hartman, PM Ashton, ZA Dyson, M Day, J Freedman, MA Chattaway, KE Holt, TJ Dallman

2019-01-01

Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typhoid fever, a systemic human infection with a burden exc..

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Seven Salmonella Typhimurium Outbreaks in Australia Linked by Trace-Back and Whole Genome Sequencing

L Ford, Q Wang, R Stafford, KA Ressler, S Norton, C Shadbolt, K Hope, N Franklin, R Krsteski, A Carswell, GP Carter, T Seemann, P Howard, M Valcanis, CFS Castillo, J Bates, K Glass, DA Williamson, V Sintchenko, BP Howden

2018-05-01

Salmonella Typhimurium is a common cause of foodborne illness in Australia. We report on seven outbreaks of Salmonella Typhimurium..

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Incorporating Whole-Genome Sequencing into Public Health Surveillance: Lessons from Prospective Sequencing of Salmonella Typhimurium in Australia

L Ford, GP Carter, Q Wang, T Seemann, V Sintchenko, K Glass, DA Williamson, P Howard, M Valcanis, CFS Castillo, M Sait, BP Howden, MD Kirk

2018-03-01

In Australia, the incidence of Salmonella Typhimurium has increased dramatically over the past decade. Whole-genome sequencing (WG..

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Increasing antimicrobial resistance in nontyphoidal salmonella isolates in Australia from 1979 to 2015

DA Williamson, CR Lane, M Easton, M Valcanis, J Strachan, MG Veitch, MD Kirk, BP Howden

2018-02-01

Australia has high and increasing rates of salmonellosis. To date, the serovar distribution and associated antimicrobial resistanc..

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